A cause of Parkinson’s disease may be a genetic mutation

The Parkinson’s disease caused by a genetic mutation? As discovered by Canadian researchers at the University of British Columbia, within an international collaboration that has involved even the USA, Asia, UK, Europe and the Middle East, would be precisely the mechanism underlying the disease degenerative that affects the central nervous system. The mutation in question, identified by the initials VPS35, Has been identified by scientists through a search performed on the DNA a family of Swiss especially predisposed to disease, As many as 11 components had developed.

Specifically, the comparison Based on sophisticated laboratory techniques was obtained from genetic material two cousins. Precisely analyzing the genetic variations, researchers were able to isolate just the gene “mutant” responsible for causing Parkinson’s disease.

The study, therefore, is to seal previous findings that had already been allowed to isolate five genes definitely linked to the onset of Parkinson’s disease. According to him, and important goal of scientific research, it appears that predisposed people develop symptoms of this progressive disease and, at the time, not curable, around the age of 50 just because of the VPS35 mutation.

The study was funded by the foundation created by American actor Michael J. Fox, impressed by their disease at a young age, and was published in the journal American Journal of Human Genetics. We hope, of course, that all these important discoveries about the causes Parkinson’s disease, that only in Italy has 200 thousand sick, sfocino then also in the development of new treatments and therapies that are able to block the progression of this disease.